Constitutive and Inducible Expression of Invasionrelated Factors in PC-3 Prostate Cancer Cells
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منابع مشابه
Constitutive and Inducible Expression of Invasion-related Factors in PC-3 Prostate Cancer Cells
BACKGROUND Tumor growth and invasion are interconnected with the tumor microenvironment. Overexpression of genes that regulate cancer cell invasion by growth factors, cytokines, and lipid factors can affect cancer aggressiveness. A comparative gene expression analysis between highly invasive and low invasive cells revealed that various genes are differentially expressed in association with inva...
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Background: Cancer is one of the most common causes of death in humans. Therefore, there is a need for new cytotoxic compounds from natural sources such as native bacteria. The current study aimed at investigating the cytotoxic effects of compounds obtained from gram-positive terricolous bacteria on the apoptosis of cells in prostate cancer (PC-3). Materials & Methods: A total of 70 s...
متن کاملCa(2+)-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells.
Prostate cancer metastasizes frequently to bone. Elevated extracellular calcium concentrations ([Ca(2+)](o)) stimulate parathyroid hormone-related protein (PTHrP) secretion from normal and malignant cells, potentially acting via the [Ca(2+)](o)-sensing receptor (CaR). Because prostate cancers produce PTHrP, if high [Ca(2+)](o) stimulates PTHrP secretion via the CaR, this could initiate a mechan...
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Prostate cancer is a devastating disease for which current therapies are inadequate. Various lines of evidences have suggested the 5-lipoxygenase (5-LOX) pathway and the leukotriene receptor pathway are potential targets for prevention or treatment of Prostate cancer. Thus, search for new anti-cancer drugs targeting 5-LOX and leukotriene is very essential and important. The objective of the pre...
متن کاملCa-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells
Sanders, Jennifer L., Naibedya Chattopadhyay, Olga Kifor, Toru Yamaguchi, and Edward M. Brown. Ca21-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells. Am J Physiol Endocrinol Metab 281: E1267–E1274, 2001.—Prostate cancer metastasizes frequently to bone. Elevated extracellular calcium concentrations ([Ca]o) stimulate parathyroid hormone-related protein (PTHrP) s...
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ژورنال
عنوان ژورنال: Journal of Cancer Prevention
سال: 2015
ISSN: 2288-3649,2288-3657
DOI: 10.15430/jcp.2015.20.2.121